pmxTools - Pharmacometric and Pharmacokinetic Toolkit
Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008) <https://web.archive.org/web/20231002021707/https://www.facm.ucl.ac.be/cooperation/Vietnam/WBI-Vietnam-October-2011/Modelling/Monolix32_PKPD_library.pdf>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).
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nonmempharmacokineticssimulation
7.33 score 37 stars 97 scripts 844 downloadsxpose.nlmixr2 - Graphical Diagnostics for Pharmacometric Models: Extension to 'nlmixr2'
Extension to 'xpose' to support 'nlmixr2'. Provides functions to import 'nlmixr2' fit data into an 'xpose' data object, allowing the use of 'xpose' for 'nlmixr2' model diagnostics.
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3.67 score 1 dependents 78 scripts 747 downloads